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The fibroblasts grow and develop extracellular matrix proteins, especially collagen

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We then examined a series of events to determine the precise step of SARS-CoV-2 entry that is blocked by clofazimine, and excluded possible effects of clofazimine on: (1) the cell-surface expression of the SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) or the MERS-CoV receptor dipeptidyl peptidase 4 (DPP4) (Extended Data Fig

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HPLC, High-performance liquid chromatography