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indeed, compared with wild-type mice, Nrf2-deficient diabetic rodents exhibited significantly greater retinal superoxide levels after 5 weeks of diabetic modeling (75)
Research suggests methylcobalamin stays in the body longer while cyanocobalamin may be more easily absorbed, but other studies have found little difference in the two in absorption and retention
Based on this, in the subsequent I/R- and TMT-induced myocardial injury model, the drug not only enhanced GSH levels and GPX and GST activities to lower oxidative damage but also reduced TMT-induced pyroptosis and I/R-mediated apoptosis [205,206,207]
doi: 10.3389/fcell.2022.976953 Received 23 June 2022 Accepted 18 July 2022 Published 10 August 2022 Volume 10 - 2022 Edited by Xinjian Zhu, Southeast University, China Reviewed by Nyzil Massey, Iowa State University, United States Manikandan Samidurai, Iowa State University, United States Updates Copyright 2022 Fabisiak and Patel
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