IF-P and CR yield distinct circulating metabolite signatures and convergence of multiple metabolic pathways To understand the potential differential impact of IF-P versus CR on the host, we surveyed the plasma metabolome, reliably detecting 136 plasma metabolites across 117 samples (i.e., QC CV 1000 in 80% of samples)
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HES (for 10 days) to CIPN rats significantly reduced PTX-induced increases in MDA, NF-B, IL-1, TNF-, COX-2, nNOS, JAK2, STAT3, and GFAP levels with neuropathic pain and alleviated endoplasmic reticulum stress (ERS) [133]
HuMSCs-derived exosomal YBX1 participates in oxidative damage repair in granulosa cells by stabilizing COX5B mRNA in an m5C-dependent manner