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In HeLa cells, GPX8 is enriched in mitochondria-associated membranes (MAMs), a critical integrating center for calcium, lipid metabolism, and redox signaling homeostasis

Am J Physiol Regul Integr Comp

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While its long been valued for its role in blood sugar regulation, a growing body of research suggests it may also help delay the aging process and extend healthy lifespan in vivo