why give vitamin b12 injections vs Pills: Richmond's Complete Guide B12 Vitamin shot - GlamourEyes

Further mechanistic studies showed that NNMTi increases intracellular NAD levels and activates the SIRT1 pathway by inhibiting NNMT, thereby suppressing the transcription of adipogenic genes and preventing the maturation of preadipocytes.This research provides a new perspective for understanding the molecular mechanism of adipocyte differentiation, confirms the key role of NNMTi in regulating adipogenesis, and lays a foundation for subsequent obesity intervention studies

You will probably NOT need to take a dedicated B12 supplement for a long period of time, but it is a good idea to ensure that you have enough to meet cellular demands

Vitamin B-12 Warnings Keep out of the reach of children and pets

For people who prefer a natural energy booster, injections avoid sugar and stimulants

FDA PCAC 2023 What this means practically for research dosage decisions: Doses above 1 mg/day are not supported by efficacy data and appear to produce diminishing returns