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Common side effects include nausea, vomiting, diarrhoea, constipation, stomach pain, headaches, and fatigue

The majority of these discontinuations were due to gastrointestinal-related adverse events, primarily occurring during the rapid dose-escalation phase

They slow down how fast your stomach empties, so you stay full longer

Ozempic is typically initiated at 0.25 mg weekly for four weeks (a non-therapeutic starter dose to improve tolerability), then increased to 0.5 mg weekly

Principal componentbased epigenetic clocks (PCHorvath1, PCHorvath2, PCHannum, PCPhenoAge, PCGrimAge) were calculated using the PC-Clocks repository ( Non-PC Horvath, Hannum, and DNAmPhenoAge clocks were calculated using the methyAge function in the ENmix R package (v1.44.3)