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Random-effects models (restricted maximum likelihood, REML) were fitted to estimate pooled log-HRs, which were then back-transformed for interpretability
10.1016/j.freeradbiomed.2008.04.007 15 BhadauriaM
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In contrast, both TDP-43 and FUS are RNA and DNA binding proteins found predominantly in the nucleus, where they regulate transcription, the DNA response, mRNA splicing, RNA stability, micro-RNA biogenesis, translation and transport, and stress granule formation (Cohen et al., 2019
FIGURE 4 3.3.1 Sirtuin activators Sirtuins also play important roles in regulating mitophagy for their deacetylation activity (Zhao N
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