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These pleiotropic actions suggest that GLP-1RAs could become valuable tools in the integrative management of patients with AITD, particularly those who also struggle with obesity, insulin resistance, or metabolic dysfunction
[55] Preclinical studies suggest semaglutide counteracts these processes by activating the AMPK and SIRT1 pathways, which are fundamental for cellular autophagy and mitophagy
This is especially beneficial for people with type 2 diabetes, but it also contributes to weight management
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