reddit switching from semaglutide to tirzepatide changing from Semaglutide to Tirzepatide: Is It a Good Idea? Switching From Tirzepatide to Semaglutide:

The action of GIP in the brain, however, also involves a decrease in appetite circuits but paradoxically would have an anti-nausea effect

Diabetes subgroup analysis actually shows slightly lower weight loss in diabetic patients (19.7% at 8mg dose) compared to non-diabetic patients (24.2% at 12mg dose)

If you are new to GLP-1 medications or have not taken one recently, you will begin with the lowest-dose Monthly Plan

Plasma semaglutide concentrations were similar in dogs undergoing pyloric ligation (to prevent intestinal absorption) compared to non-ligated dogs, with plasma concentrations in the splenic vein being significantly higher than in the portal vein, providing further evidence that the stomach is the site of absorption

A large study conducted by the manufacturer of a leading GLP-1 medication found that people who discontinued semaglutide gained back an average of two-thirds of the weight they lost in just one year