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Regarding participant characteristics, the majority of studies enrolled overweight or obese adults with type 2 diabetes, or those receiving glucose-lowering treatments such as metformin, SGLT2 inhibitors, DPP-4 inhibitors, or insulin

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Furthermore, we did not use operationalized criteria (for example, Diagnostic and Statistical Manual 5th edition) to define the populations of interest because these would not be applicable across animal and human studies, but instead relied on the definitions provided by the individual articles

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We turn to Houston-based Aestheticians Ashley Darbonne and Krys Givens for their professional insights about this nonsurgical skin tightening treatment