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BMI of 28 kg/m or 24 kg/m with at least one weight-related comorbidity (such as hypertension, hyperglycaemia, sleep apnoea syndrome, dyslipidaemia and cardiovascular disease)

Studies have found that GLP-1R is widely distributed on pancreatic and other tissues and has multiple biological effects, such as reducing neuroinflammation, promoting nerve growth, improving heart function, suppressing appetite, delaying gastric emptying, regulating blood lipid metabolism and reducing fat deposition

Other reported adverse reactions include allergic reactions, cardiovascular, psychiatric and thyroid-related events, as well as biliary diseases and pancreatitis (179,180)

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Managing Oxidative Stress Naturally Beyond supplements and diet, managing oxidative stress involves looking at your environment