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The semaglutide group showed a significantly improved Kansas City Cardiomyopathy Questionnaire clinical summary score and a longer 6-min walking distance from baseline (21.5 m and 1.2 m in the semaglutide and placebo groups, respectively, intergroup difference 20.3 m, 95% CI 8.632.1 m), compared with that in the placebo group despite the relatively short observation period of 52 weeks

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In the second and third group each of the bone defects was treated locally with either 2 ml autologous bone marrow (7 th post-operative day) or TRIS-BPC157 (10 g/kg b.w

Intravenous administration might be better in some cases