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About 18% of people had ongoing symptoms during the 72-week trial, and in most of these cases, their Wegovy dose was not reduced or stopped

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Furthermore, a dependence on the use of metformin as a prophylactic to delay aging could serve to decrease the incentive to pursue the proven benefits of lifestyle changes such as improved diet and exercise

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In experimental settings, retatrutide influences biological processes related to metabolism and hormonal signaling