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Abstract Background: Obesity, a multifactorial disorder with pandemic dimensions, is conceded a major culprit of morbidity and mortality worldwide, necessitating efficient therapeutic strategies

The role of membrane proteolysis, particularly through pathways such as ERAD and intramembrane proteolysis, is crucial for cardiovascular health

Controlled ovarian stimulation medicines (e.g., clomiphene, letrozole, gonadotropins) take rapid effect to initiate ovulation and need clinical supervision and monitoring

The enzyme analyses were carried out using commercially available kits in accordance with the manufacturers instructions (BioVision, Milpitas, CA, USA)

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