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Primer sequences are shown in Supplementary Table S2

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Of note, pharmacologically induced PFC NMDAR hypofunction leads to increased oscillations [99] while genetic deletion of NMDAR1 subunits in pyramidal neurons increases oscillations, cell excitability and sEPSC frequency [100], similar to the present data

New entrants to this market could drive prices down, but I worry that if a few companies continue to represent virtually all of the market, they will maintain their price discipline and the costs of these medications will leave them out of reach for many who could benefit from them