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Safety and tolerability The most frequently observed adverse events (AEs) following start of treatment were gastrointestinal disorders observed in 10 of 13 patients (Table 1)

This may be related to the fact that renal denervation reduces sympathetic nerve activity and catecholamine levels throughout the body, and it is precisely these systemic changes that ultimately affect the signal transduction pathways of the heart

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This process not only assists in fat loss but also enhances physical performance and recovery