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Satiation gradually rises during a meal event as hunger diminishes, peaking at meal termination

16 Figure 3: Risk of OACs in patients on GLP-1s versus patients on insulin Conclusion GLP-1s, initially developed to help manage and treat diabetes and later used to treat obesity, are now showing significant potential to help prevent and treat CVD, mental health disorders, liver and kidney disorders, neurodegenerative disorders, addiction disorders, and cancer

Clonidine is a medication commonly prescribed to treat high blood pressure, attention deficit hyperactivity disorder (ADHD), and certain pain conditions