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TAMs have been demonstrated to create a vessel network that provides the tumour mass with much-needed nutrient supply for sustenance and VEGF-A, thereby resulting in resistant tumour cells [77, 78]

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Reactive oxygen species as potential antiviral targets

5.2.5 Future directions: targeting cell-type specific ferroptosis programs Emerging single-cell and spatial transcriptomic analyses have revealed that ferroptosis susceptibility varies significantly among different joint-resident cells in OA