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Once someone has done all the right things for nutrition, fitness, sleep, stress management, and frailty prevention, then having a conversation about adding a pharmacologic option for longevity or optimization becomes appropriate. The Takeaway GLP-1 medications, like semaglutide and tirzepatide, were originally developed for diabetes, but researchers are now exploring if they may extend lifespan and help people maintain good health for a longer period of time

The European Medicines Agency's Pharmacovigilance Risk Assessment Committee (PRAC) has identified ileus as an adverse reaction associated with GLP-1 receptor agonists, making this a recognised rather than merely theoretical risk

From the Social Value Act (2012) to the Procurement Act (2023), expectations have steadily risen

Bashar T, Akhter N

Remember, individual results can vary based on factors like metabolism, diet, and exercise levels