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GSH could detoxify heterogeneous substances under the catalysis of Glutathione S-transferases (GST), then secrete them via the multidrug resistance associated proteins (MRPs) efflux pump ( 3 GSH-responsive and -exhausting metal nanomaterials 3.1 Inorganic nanomaterials Inorganic nanomaterials that have intrinsically unique physicochemical properties and can provide satisfactory functionality show enormous potential in biomedical applications, especially in cancer therapy ( 2 O 2 , realizing tumor-specific catalytic therapy with response to the TME featuring overexpressed GSH and H 2 O 2 (Yin et al., 2019)

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OCPs decrease the endometrial lining and thus decrease the amount of tissue that produces prostaglandins

The skin is constantly regenerating, which means the pigmented cells will naturally slough off

Both treatments restored GPX4 expression, indicating that celastrol alleviated ferroptosis sensitivity in HK-2 cells under HG conditions