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Tirzepatide: The Dual-Hormone Innovation Tirzepatide (brand names Mounjaro and Zepbound) represents a newer approach

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This aligns with other studies that have analyzed the efficacy of pharmacological treatments for HFpEF, which have shown significant heterogeneity in HF hospitalization events among the studies.18 Other than HF hospitalization, the primary outcomes include cardiovascular mortality

Thirdly, the objective of treating obesity extends beyond weight loss to include the prevention of obesity-related complications and improvements in comorbid conditions, as evidenced by positive changes in cardiometabolic risk factors observed in Phase 3 clinical trials [87]