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Reduced manganese superoxide dismutase (MnSOD) activity, reduced glutathione to glutathione disulphide (GSH/GSSG) ratios, and an impaired oxidative phosphorylation system were accompanied by an increase in caspase 9 activity in hippocampal homogenates

Food and Drug Administration (FDA) regulates mushroom-based products primarily as dietary supplements under the Dietary Supplement Health and Education Act (DSHEA)

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Similarly, cyclophosphamide, a widely used chemotherapeutic agent, inhibits autophagy while simultaneously triggering apoptosis and pyroptosis, ultimately leading to DOR (Liu W