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The pathophysiology of ME/CFS is complex, involving immune system alterations, increased oxidative stress, impaired natural killer (NK) cells and B cells, autoimmunity, and neuroinflammation

These results suggest that NAC can alleviate genotoxic stress and apoptosis triggered by environmental toxins, thereby underscoring its therapeutic potential in maintaining genomic integrity and neuronal function in oxidative environments [10]

For others, theyre a sign of an underlying issue, like a vitamin deficiency, a fungal infection, or even a condition like vitiligo