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Targeting of the two GLS isoforms, GLS-1 and GLS-2, will provide new insights on the treatment of leukemia

Khan M, Maryam A, Mehmood T et al (2015) Enhancing activity of anticancer drugs in multidrug resistant tumors by modulating P-glycoprotein through dietary nutraceuticals

Intestine-specific overexpression of carboxylesterase 2c protects mice from diet-induced liver steatosis and obesity

These findings reveal a novel mechanism for regulating ferroptosis and hold significant implications for developing treatments for ferroptosis-related diseases, such as cancer and ischemiareperfusion injury (67)