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Semaglutide and tirzepatide are not metabolized through cytochrome P450 enzymes, so they dont affect bupropion metabolism

Additionally, dehydration from gastrointestinal side effects may increase the risk of acute kidney injury, and gallbladder disease has been reported with incretin-based therapies

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The number of sessions depends on the age of the patient so if your age group is between 28 and 30 one session every three weeks (3-4 procedures) will be the ideal ratio, while if you are aged between 30 and 35 one session every two weeks (3-4 procedures) is the perfect number

Zheng et al., 2006)