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The ecto-enzymes CD39 and CD73, expressed on Tregs, catalyze the metabolism of ATP (Adenosine triphosphate) into AMP (Adenosine monophosphate) and in turn, produce the immunoregulatory purine, adenosine ( in vivo ( 3) Induction of apoptosis

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In contrast to earlier inconclusive evidence, we show that 2M does not bind Cu(II) ions

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