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The deprotecting agent for Fmoc deprotection is selected from bases such as piperidine, piperazine, DBU optionally in presence of a solvent such as DMF, NMP and the like
TEXT ON-SCREEN: Always use a new needle for each injection
The investment required for proper storage is minimal
Wegovy comes as a prefilled, single-dose pen with the following recommended storage guidelines : Store unused Wegovy in the refrigerator (36F 46F), where it stays good until its labeled expiration date
Step 4: Preparation of Resin bound Semaglutide backbone Boc-His(Trt)-Aib-OH compound of formula-2 (26.93 gm) was dissolved in NMP (150 ml) and DMF (100 ml) at 25-30C and HOBt (6.23 gm), DIC (7.23 ml) and DIPEA (4.84 ml) were added to the reaction mixture at the same temperature
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