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Overall, the reduction was modest but meaningful at the population level, amounting to about 7 fewer cases of any substance use disorder (including nicotine) for every 1,000 people treated
DOI: 10.2337/dc16-0917
Pediatrics (2015) 136:e2679
However, GLP-1 receptor agonists had no significant effects on the occurrence of thyroid cancer (RR 1.30, 95% CI 0.86-1.97), hyperthyroidism (RR 1.19, 95% CI 0.61-2.35), hypothyroidism (RR 1.22, 95% CI 0.80-1.87), thyroiditis (RR 1.83, 95% CI 0.51-6.57), thyroid mass (RR 1.17, 95% CI 0.43-3.20), and goiter (RR 1.17, 95% CI 0.74-1.86)