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In general, plants own very competent enzymatic [catalase (CAT), monodehydroascorbate reductase (MDHAR), superoxide dismutase (SOD), ascorbate peroxidase (APX), glutathione reductase (GR), dehydroascorbate reductase (DHAR), guaiacol peroxidase (GPX)] and non-enzymatic [glutathione (GSH), ascorbic acid (AsA), carotenoids, alkaloids, phenolic compounds as well as non-proteinaceous amino acids] antioxidative defensive systems which act in collaboration to regulate the problems of unrestrained oxidation and ultimately shield the plant cells from oxidants injury by scavenging these toxic ROS [11]

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Recent studies have reported that chrysin mitigates inflammatory cell infiltration and histopathological alterations in AD mouse model, potentially via suppression of the NF-B signaling pathway and downregulation of CCL5 expression (Yeo et al., 2020)

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