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Nevertheless, a recent study has confirmed the presence of NCC in some but not all insulin-positive -cells of both human and rodent islets (Zhang et al., 2022b)

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MET activation is thus involved in brain plasticity, as suggested by the fact that HGF administration on hippocampal slices enhances the phosphorylation of the glutamatergic NMDA receptor subunit GluN1, augments the NMDA-mediated currents, and increases the amplitude of long-term potentiation (LTP) induced by elevated neuronal activity (Kato et al., 2012)

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