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Iron chelators Deferoxamine (DFO), ciclopirox olamine (CPX), 2,2-bipyridyl and other iron chelators can directly bind free iron, maintain the balance of iron metabolism in vivo and inhibit ferroptosis induced by erastin (Fig

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Meta-analyses show that supplementation is a safe and effective way to increase muscle creatine concentrations, promoting the associated benefits

This review has highlighted how neuroinflammation, oxidative stress, mitochondrial dysfunction, and impaired proteostasis converge to create a vicious cycle that overwhelms neuronal resilience

Additionally, polyphenols interact with gut microbial strains, which can alter their molecular states and affect their subsequent bioactivity (106)