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Part of it is weight [loss], but other factors may be contributing as well better glycemic controls, anti-inflammatory effects. More research is necessary and inevitable especially studies looking at the newer weight-loss formulations of GLP-1 medications, says Benjamin Liu, another resident physician at Case Western and co-author of the ASCO study

Current approved treatments, including acetylcholinesterase inhibitors and the N -methyl- D -aspartate receptor (NMDAR) antagonist memantine, offer only modest symptomatic relief without altering disease progression

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Pennings provides expert insight into the mechanism of these new medications