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This process can reduce the concentration of orthodiphenols and lead to their depletion, especially in our experimental conditions where the grape must was diluted five times

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Protocatechuic acid is a simple phenolic acid derived from Nidus vespae that has antioxidant, bacteriostatic, antitumour and neuroprotective effects

In the computational study, no support was found for the hypothesis that a water molecule could serve as an alternative to Tyr9 as a proton donor ( 1 loss of binding energy due to the absence of the glycine residue