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Lancet Diabetes Endocrinol 7(10):776785 Vilsbll T, Christensen M, Junker AE, Knop FK, Gluud LL (2012) Effects of glucagon-like peptide-1 receptor agonists on weight loss: systematic review and meta-analyses of randomised controlled trials

This has potential to alleviate supply shortages currently plaguing the class, and may provide an opportunity for Lilly to bring a lower-cost option to market, though Lillys pricing strategy for orforglipron is unknown and likely to be dependent upon clinical results

Semaglutide (Wegovy) single-use pens may be stored at temperatures up to 30C for up to 6 weeks before use

Although these may be potential side effects, the success rate concerning these treatments is very high, and most patients will achieve symptom relief and normalized thyroid hormone levels (Scarabosio et al

-This drug has not been studied in patients with a history of pancreatitis and therefore, other therapies should be considered in these patients