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Missing values in the dataset were imputed via iterative imputation using a Bayesian Ridge regression on log-transformed data, with performance evaluated through root mean square error (RMSE), mean absolute error (MAE) and KolmogorovSmirnov tests

The most commonly used DMARDs are: METHOTREXATE ( Non-Biologic ): it can be taken orally, has antiinflammatory effects and reduces the number of activated T cells and TNF- levels

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[4] While common, it is important to note that these events are generally mildtomoderate, and they are also often transient, occurring most frequently during or shortly after dose escalation

medication adherence is the most important factor in achieving sustainable results (Polonsky et al., Diabetes Care , 2020)