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[DOI] [PMC free article] [PubMed] [Google Scholar] Emmanouilidis L

When G6PD activity is reduced or absent, red blood cells become highly vulnerable to oxidative stress

One large review of eight studies found that supplementation with BCAAs was able to reduce muscle soreness and improve muscle function following intense workouts

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Another promising approach is gene therapy that targets hepatocytes harboring mutated porphobilinogen deaminase ( PBGD ) gene ( Brain Iron Accumulation Diseases Neurodegeneration with brain iron accumulation (NBIA) is a group of genetic diseases characterized by movement disorders such as parkinsonism and dystonia, psychomotor delay, and early death