glp 1 approved for osa Indications GLP-1/GIP RA Summary Sheet and Beyond! Glp-1/Zepbound for Sleep Apnea Treatment

Sorry for stating the obvious but have you considered changing injection sites

However, all these treatments are symptomatic and cannot prevent or reverse AD pathology ( Figure 1 ) ( Figure 1 Biological characteristics of GLP-1 In the 1980s, a new glucagon-like peptide, produced from proglucagon cleavage, was discovered to stimulate insulin secretion ( GLP-1, a 36-amino acid peptide, is produced in enteroendocrine L-cells of the distal small bowel and colon ( The effect of GLP-1 depends on blood glucose levels since it can only potentiate glucose-stimulated insulin secretion from islet beta cells in the hyperglycemic state rather than in the normal blood glucose state (98101)

Nov-Dec 2022;75:59-68

Injection site rotation (abdomen, thigh, upper arm) prevents localised irritation, and 29-gauge insulin syringes make subcutaneous administration nearly painless

Aronne LJ, Horn DB, le Roux CW, et al