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Description

Oral L-citrulline has high intestinal absorption but minimal first-pass metabolism and renal reabsorption (Shearer et al., 1997)

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doi: 10.1038/ijo.2014.177 19 AlbaMYeeJFrustaciMESamtaniMNFleckP

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This decoupling a short-lived peptide carrying a persistent metal is the key pharmacological feature of systemic GHK-Cu and the reason copper balance, not peptide half-life, is the dominant safety consideration

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aroma, sweeteners: sucralose, acesulfame K

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Small intestinal transit time

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