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15 The efficacy of rifaximin was evaluated in a meta-analysis of five RCTs comparing rifaximin and NADs for treatment of HE

B12 deficiency can lead to severe and potentially irreversible neurological damage if misdiagnosed or inadequately treated

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Downregulation of Connexin 43 promotes vascular cell loss and excess permeability associated with the development of vascular lesions in the diabetic retina

Pending this data, antioxidants should be considered on a case-by-case basis in patients with AD according to disease activity and severity, comorbidities, patient preferences, and drug interactions