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Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
Fatigue and Weakness : Chronic fatigue can sometimes be attributed to low levels of B-vitamins, which are critical in energy metabolism
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Physically, midsection weight gain puts strain on the joints and lower back, making it harder to stay active and comfortable
Indeed, islets from young mice lacking NCC or NDCBE (NCC KO or NDCBE KO , respectively) exhibited normal secretory responses to glucose (Kucharczyk et al., 2023)
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