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This architecture creates an extraordinarily high binding affinity (pK = 16.44), roughly 10 million times stronger than other tripeptides and comparable to albumins copper binding

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All doses markedly suppressed food intake compared to vehicle controls, with the 30 and 300 nmol/kg doses producing the strongest anorectic effects, reducing 24-hour food intake by 51% and 57%, respectively

My appointment was short, maybe 10 minutes