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As an analog of endogenous amylin, it is studied for its receptor-mediated signaling dynamics, sustained activation profile, and downstream neuroendocrine cascades within controlled laboratory environments

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These may include nausea, reduced appetite, or temporary changes in bowel habits as the body adapts to altered digestion

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Another study showed that DFO could suppress excessive collagenase-mediated type II collagen cleavage and protease, production of cytokine, and COL10A1 expression while upregulating adenosine monophosphate-activated protein kinase and Krebs cycle genes in human osteoarthritic cartilage [125]