So, if histamines are a natural immune response, why do some people develop a histamine intolerance
R., Scheff, S
Moreover, the fatsoluble vitamin influences the human microbiota by retaining intestinal homeostasis accomplished due to an increased cellular production of antimicrobial proteins from, for example macrophages and monocytes through RXR/VDR-signaling induction of promotor sequences of cathelicidin antimicrobial peptide etc., thereby preventing intestinal bacterial translocation and, on a large scale, the development of auto-inflammatory / metabolic dysfunctions, along with its role in maintaining intestinal epithelial cell integrity (production of nitric oxide due to upregulation of endothelial nitric oxide synthase (eNOS)), which in turn minimizes epithelial damage caused by bacterial lipopolysaccharides (LPS) [151, 162,163,164,165,166,167,168]
What to Expect : The injection procedure is quick and somewhat painless
Wang B-H, Ou-Yang J-P
