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Hcy is implicated in cardiovascular disease through diverse mechanisms, including the heightened proliferation of muscle cells leading to vessel constriction, modification of blood coagulation properties, oxidative damage to the vascular endothelium, and harm to arterial walls [49]

Blood pressure reactivity to stress (cold pressor test) was significantly attenuated in the combination group compared to both placebo and L-citrulline alone

Together, the evidence has demonstrated an association between traits of GD and higher levels of autistic traits and greater rates of autism diagnoses (see Glidden et al

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