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In the absence of glp-1 , LAG-1::HA level was reduced throughout the progenitor zone, with a gradual rise from distal to proximal

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Upon nutrient ingestion GLP-1 is secreted into the blood from intestinal enteroendocrine L-cells that are found predominantly in the distal ileum and proximal colon with some production from these cell types in the duodenum and jejunum

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