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Consequently, TGF-s role in PCa cells is complex, exhibiting tumor-inhibitory effects in early stages and tumor-promoting effects in advanced stages, along with its immunosuppressive function ( 3 Igniting immunogenic cell death in prostate cancer cells with peptides Promoting tumor cell apoptosis is a common anti-cancer strategy

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278 However, in T cells, Asn can enhance the antitumor effect of CD8 + T cells by binding to the SRC family protein tyrosinase LCK and assisting LCK to phosphorylate at Tyr394 and 505, thereby enhancing the activity of Lck starved T cell receptor signaling pathway