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The Mounjaro FDA prescribing information does not list local injection-site reactions on their own as a reason to discontinue

Mody R, Valentine WJ, Hoog M, Sharland H, Belger M

Instead of being swallowed and absorbed through the gastrointestinal tract (where most peptides get destroyed by digestive enzymes), the tablet dissolves on the tongue and is absorbed through the oral mucosa

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