Quick Takeaways Tesamorelin has robust clinical evidence for reducing visceral fat (15-17.5%), increasing lean mass (1.42 kg), and improving metabolic markers in human trials Ipamorelin selectively releases growth hormone without affecting cortisol or prolactin, making it the cleanest GHRP available Combining a GHRH with a GHRP creates synergistic GH pulsatility that mimics and amplifies your bodys natural growth hormone patterns My recommended protocol: Tesamorelin 1mg + Ipamorelin 100mcg, injected AM/PM, 5 days on/2 days off, 8 weeks on/8 weeks off What This Peptide Combination Actually Is Tesamorelin and Ipamorelin target different receptors in the growth hormone regulation system, which is precisely why they work so well together
Individuals who are pregnant, nursing, under 18 years of age, taking medications, or managing a medical condition should consult their healthcare practitioner before use
Formal rulemaking follows after
That smaller pulse is also why community sources commonly describe sermorelin as the conservative on-ramp for users new to GH peptides
Telehealth startups advertise quick scripts, but legitimate prescribers will screen you for contraindications (thyroid tumors, pancreatitis history) and monitor labs