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Nevertheless, the insulin resistance and abdominal adiposity seems to be essential in the pathophysiological process, and for this reason, based on the information available, we propose IGF-1 as a key hormone in the pathophysiology of metabolic syndrome due to its implications in the metabolism of carbohydrates and lipids

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Patients should be particularly vigilant about monitoring for gastrointestinal side effects, such as nausea or diarrhea, and report any persistent symptoms to their healthcare provider