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The lysine residues undergo many post-translational modifications, including ubiquitination, SUMOylation and acetylation, which are vital for cell survival and proliferation [70]

A 2020 retrospective cohort study (N = 4,072) of patients with gout found that urate-lowering treatment reduced the relative risks of coronary artery disease and stroke by ~30% compared with no treatment

In conclusion, antioxidant and micronutrient supplements have been widely studied and proven to enhance fertility parameters in both men and women, increasing the chances of conception

ROS are byproducts of normal oxygen metabolism and act as inflammatory mediators that regulate cell proliferation but can also exert harmful effects [25]

Efficacy and safety of tirzepatide, dual GLP-1/GIP receptor agonists, in the management of type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials